TeXshade is alignment shading software completely written in TeX/LaTeX; it can process multiple sequence alignments in the .MSF and the .ALN file formats. In addition to common shading algorithms, it provides special shading modes showing functional aspects, e.g. charge or hydropathy, and a wide range of commands for handling shading colours, text styles, labels, legends; it even allows the user to define completely new shading modes. TeXshade combines highest flexibility with TeX output quality — all in a bundle that does not demand excessive development time of the user.